A Combination Chemotherapy Protocol (VELCAP-L) for Dogs with Lymphoma   总被引：3，自引：1，他引：2  

Barbara I. Zemann  Antony S. Moore  William M. Rand  Gail Mason  David M. Ruslander  Angela E. Frimberger  Carrie A. Wood  Deborah A. L'Heureux  John Gliatto  Susan M. Cotter 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1998,12(6):465-470

Ninety-eight dogs with lymphoma treated with a 5-drug combination chemotherapy regimen (vincristine, L-asparaginase. cyclophosphamide, doxorubicin, prednisone [VELCAP-L]) were evaluated for pretreatment characteristics predictive for response and remission duration. The complete remission rate was 69%, with a median remission duration of 55 weeks. Dogs with advanced stage of disease, constitutional signs, dogs that were older, and dogs that were dyspneic were less likely to achieve remission. Once in remission, small dogs and dogs without pretreatment thrombocytopenia were likely to have longer remission duration. Toxicoses were frequent, but rarely fatal, and no predictitive factors were found for a dog developing toxicoses. VELCAP-L is an effective treatment for dogs in stage I-III lymphoma, particularly in young, small animals.  相似文献   

Hyperthyroidism Associated with a Thyroid Adenocarcinoma in a 21-Year-Old Gelding     

Sammy Ramirez  Jill J. McClure  Rustin M. Moore  Karen J. Wolfsheimer  Stephen D. Gaunt  Mustajab H. Mirza  Wayne Taylor 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1998,12(6):475-477

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Presumed lipid retinopathy in a diabetic dog     

Halenda RM  Moore CP 《Veterinary ophthalmology》1998,1(2-3):171-174

An eight-year-old neutered male diabetic Cardigan Welsh Corgi was presented for bilateral mature cataracts. Phacoemulsification and intraocular lens implantation were performed routinely, and recovery was uneventful for several months except for lipemic aqueous flare which gradually resolved during the postoperative period. Five months following surgery the owner presented the dog for decreased vision. White retinal deposits were visualized ophthalmoscopically. Serum analysis revealed that the dog was concurrently markedly hyperlipemic. The patient's diet was changed from a high- to a low-fat diet, following which diabetes control improved, hyperlipemia resolved, and the retinal deposits decreased markedly in size. The retinal deposits seen ophthalmoscopically are presumed to be lipid based upon their association with marked hyperlipemia, and the concurrent resolution of hyperlipemia and the fundic lesions.  相似文献   

Hemorrhage from the cosmetic otoplasty of Doberman Pinschers with von Willebrand's disease   总被引：3，自引：0，他引：3  

G S Johnson  G T Schlink  R K Fallon  C P Moore 《American journal of veterinary research》1985,46(6):1335-1340

The hemorrhagic tendencies of 23 Doberman Pinscher pups were observed during cosmetic otoplasty and were ranked by a +1 to +4 grading system (+1 = least hemorrhage, and +4 = most hemorrhage). A second estimate of the hemostatic competencies of these dogs was made by counting the gauze sponges used in the otoplasties. Factor VIII-related antigen concentrations and coagglutinin cofactor concentrations were measured in plasma samples from blood drawn not more than 30 hours before the surgical procedures were done. The factor VIII-related antigen concentrations were between 9% and 147% of the concentration in a normal plasma pool, and the coagglutinin cofactor concentrations were between 1% and 165%, indicating that some of these dogs had von Willebrand's disease. The hemorrhagic tendencies of 12 pups were graded +1. This group had a mean antigen concentration of 75% (min-max, 38% to 147%) and a mean coagglutinin cofactor concentration of 89% (min-max, 42% to 165%). These were significantly greater than the antigen and cofactor concentrations of the grades +2 (n = 5), +3 (n = 3), or +4 (n = 3) dogs. Significant differences were not found when antigen concentrations of the grade +2 dogs (mean, 16%; min-max, 11% to 22%), grade +3 dogs (mean, 13%; 12% to 16%), and grade +4 dogs (mean, 11%; 9% to 12%) were compared with each other, nor were significant differences seen among the coagglutinin cofactor concentrations of the grade +2 dogs (mean, 7%; min-max, 1% to 11%), grade +3 dogs (mean, 6%, 4% to 8%), and grade +4 dogs (mean, 5%; 2% to 9%).(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

Sectional notes     

J. G. Milward  H. C. Moore 《American Journal of Potato Research》1933,10(5):100-101

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Bluetongue and related viruses in Ibadan, Nigeria: serologic comparison of bluetongue, epizootic hemorrhagic disease of deer, and Abadina (Palyam) viral isolates     

D L Moore 《American journal of veterinary research》1974,35(8):1109-1113

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Crop and market news     

B. A. Brown  K. P. Bemis  E. A. Stokdyk  G. D. Clark  H. C. Moore  A. G. Tolaas  H. O. Werner  Wm. Martin  E. V. Hardenburg  W. K. McCulock  H. H. Zimmerly  J. G. Milward 《American Journal of Potato Research》1926,3(7):247-260

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Identification and anatomic categorization of the vascular patterns to the pelvic limb muscles of dogs     

J N Chambers  P T Purinton  S W Allen  J L Moore 《American journal of veterinary research》1990,51(2):305-313

The vascular patterns to pelvic limb muscles were studied in 6 dogs (12 limbs) to identify muscles most suitable for transposition in the treatment of large wounds. Gross dissection of injected specimens and angiography were used to identify the vascular pedicles. The vascular pedicles to several muscles were generally consistent, and any variations would not interfere with most muscle transfers. The cranial part of the sartorius, gracillis, semitendinosus, and rectus femoris muscles were identified as suitable candidates for transfer. The caudal part of the sartorius, cranial tibial, and long digital extensor muscles have segmentalized vascular patterns that would limit its arc of rotation.  相似文献   

Sectional notes     

H. W. Poulsen  H. G. Zuckerman  C. H. Metzger  W. B. Ward  W. C. Edmundson  E. R. Bennet  R. A. Jehle  A. B. Beaumont  John S. Gardner  E. L. Newdick  Frank W. Hussey  E. J. Wheeler  H. C. Moore  Marx Koehnke  A. G. Tolaas  E. E. Isaac  H. O. Werner  O. Butler  William H. Martin  K. H. Fernow  E. R. Jackman  E. B. Tussing  E. V. Hardenburg  J. B. R. Dickey  K. H. Klages  G. S. Ralston  H. L. Bailey  John Tucker 《American Journal of Potato Research》1934,11(8):207-226

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“The seed plot an important factor in seed potato certification”     

H. C. Moore 《American Journal of Potato Research》1926,3(10):323-325

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